Xenon Pharmaceuticals logo

Xenon Pharmaceuticals

Biotechnology & Life SciencesNasdaq: XENEBurnaby, BC

Burnaby-based neuroscience-focused biopharmaceutical company discovering and developing ion-channel-modulating therapeutics for neurological and psychiatric disorders.

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Xenon Pharmaceuticals describes itself as a neuroscience-focused biopharmaceutical company dedicated to delivering life-changing therapeutics for people in need. Founded in 1996 with a focus on discovering new genetic targets to treat human disease, it develops ion-channel-modulating therapeutics for neurological and psychiatric disorders.

  • Its X-TOLE2 study of azetukalner in focal onset seizures completed enrollment with 380 patients, with a topline readout anticipated in the first half of 2026. sec.gov

  • NBI-921355, partnered with Neurocrine, advanced into a Phase 1 study in February 2025, triggering a $7.5M milestone payment to Xenon. sec.gov

  • Initiated two Phase 1 studies in 2025 for pain candidates XEN1701 (Nav1.7) and XEN1120 (Kv7), with completion expected in 2026. sec.gov

  • States it was founded in 1996 with a focus on discovering new genetic targets to treat human disease. xenon-pharma.com

Products & Services

Company site: xenon-pharma.com

Products Xenon Pharmaceuticals publishes on its own site. Each card links to the page it was taken from.

Azetukalner

Phase 3

Kv7 potassium channel opener listed at Phase 3 for focal onset seizures, bipolar depression, major depressive disorder and generalized seizures.

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XEN1701

Phase 1

Nav1.7 sodium channel programme for pain, listed at Phase 1.

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XEN1120

Phase 1

Kv7 programme for pain, listed at Phase 1.

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Partnerships

Publicly announced partnerships.

Neurocrine Biosciences

NBI-921355 advanced into a Phase 1 study in February 2025 under the Neurocrine collaboration, triggering a $7.5M milestone payment to Xenon.

People

Sourced from the company's own pages or announcements.

Ian Mortimer

President and Chief Executive Officer

Tucker Kelly

Chief Financial Officer

Chris Kenney

Chief Medical Officer

Matthew D. Ronsheim

Chief Operating Officer

Technology Focus

Company site: xenon-pharma.com

Terms the company uses about its own work.

Ion channel modulationKv7 potassium channelNav1.7 sodium channelEpilepsy therapeuticsPsychiatric therapeuticsPain therapeutics

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